VerySweatyBetty.com

If the trials all go well we could be seeing a new topical agent coming to us sufferers soon.

Want to thank my dearest friend for keeping us in the loop of new things for Hyperhidosis, your a gem

NEW ANTIPERSPIRANT HYDROGEL WITH ACETYLCHOLINE BLOCKING
MECHANISM: FIRST CLINICAL REPORT
INTRODUCTION AND DESCRIPTION OF THE NEW ANTIPERSPIRANT GEL

A new antiperspirant hydrogel has been projected and discovered based on an innovative
mechanism of action consisting on acetylcholine release partial blocking. This biochemical
mechanism is the main involved in eccrine sweat glands secretion and is the main issue to solve in
the patients suffering of hyperhidrosis. Generally patients suffering of moderate to severe grade
hyperhidrosis undergo to botulinum toxin sessions properly to block acetylcholine release and so
reduce sweating for several months and furthermore apply day by day very high percentage of
Aluminum chloride topical products to reduce excessive sweating. Botulinum Toxin is very
effective because blocks specifically proteins which induce acetylcholine release and so reduce
dramatically eccrine glands secretion; unfortunately injection of botulinum toxin is a strict specialist
medical practice and is not free from side effects, contraindications, allergic events and so on. Not
all the patients could be enrolled to apply botulinum toxin and many times these patients, impatient
to solve their embarrassing condition, provide to buy this drug from not legal channels and accept
to be treated from not specialized and skilled people. Furthermore, in the cosmetic landscape,
there’s only aluminum chloride products capable to produce acceptable results, but they are not free
from side effects as adenitis and skin irritations if applied every day.
This new cosmetic approach to hyperhidrosis has the main purpose to give an important opportunity
to all the patients suffering of hyperhidrosis allowing them to treat this condition with the same
mechanism of action of botulinum toxin, but without inject anything and simply applying a pleasant
and light hydrogel in the axilla, face, hands and forehead.
This gel contains an association of natural substances capable to reduce acetylcholine release in the
proximity of eccrine glands reducing contextually their secretion, exactly as botulinum toxin, but in
a very natural and not invasive way.
PRELIMINARY CLINICAL REPORT
20 patients suffering of moderate to severe grade hyperhydrosis have been tested under the
supervision of specialized dermatologists in the San Gallicano Hospital Dermatology Department in
Rome.
These patients began application of this new gel (SNARE BLOCK), after two weeks from the
interruption of application of any other product for hyperhidrosis (aluminum chloride, long lasting
antiperspirant products etc.): they only applied short lasting deodorants and a common hygiene
protocol.
These patients were educated to apply SNARE BLOCK two times a day (morning and night) in the
affected area taking care to induce a complete absorption of the gel in the skin area involved with a
light massage. No other products for hyperhydrosis were applied with the exception of common
deodorants with no antiperspirant molecules inside.
These patients came back to the clinic once a week to compile a clinical report under supervision of
a dermatologist in charge to carry out the clinical evaluation.
The parameters considered were:
- Grade of subjective satisfaction;
- Grade of pleasantness of application;
- Indication of “sweat reduction grade” in a graduated scale;
- Fast working effect grade;
- Objective clinical examination;
At the end of the 4 weeks, 18 patients declared to be:
- quite satisfied to highly satisfied of the efficacy of the product indicating a grade of “sweat
reduction” ranging from 6 to 8 in a graduated scale ranging from 0 for no effects to 10 for complete
satisfaction. 1 patient interrupted after only 2 weeks declaring that the product didn’t work and
another one interrupted after 3 weeks with no explanations;
- in a scale ranging from 0 to 10 for the “sweat reduction” parameter grade 2 patients reported a
score of 8 (high grade of reduction), 13 patients reported a score of 7 (moderate-high grade of
reduction); 3 patients reported a score of 4-5 (moderate grade of reduction);
- 16 patients declared to be satisfied in terms of pleasantness in a scale reporting these parameters: 2
patients not satisfied (bad sensorial effect in the skin), 7 patients moderately satisfied (acceptable
sensorial effect, but not very nice), 9 very satisfied (very good skin effect and nice to apply);
- 18 patients declared a quite slow working effect onset: 7 patients declared to feel first working
effect in sweating only after 15 days from the first application and the best effect after 18-20 days.

Please join us in our friendly forum on more about this new and exciting product, feel free to leave your questions and comments.  

Forum link

How Compensatory Sweating works:

The current train of thought is that our own inbuilt thermometer is faulty. This is called the Hypothalamus and it’s tucked away in the brain. This is what causes us to overheat. When the body’s temperature rises by 4 degrees C, we become disorientated and confused. By the time we reach 7 degrees C, we’d be dead. Because the body is such an amazing feat of natural engineering, we have an inbuilt sprinkler system to prevent us from overheating and to keep us alive. This is where the sweating comes from. When you block off any area of sweating, that’s all you’re doing. You’re not cooling yourself down. As you’re still hot, you’ll still be sweating until you cool down, it’s just that the sweat will appear in other areas and it’ll take longer to cool down as your sweating is limited. Blocking sweat is not the best way of dealing with it, although we all need to block in the odd area or two – ie underarms etc. It’s always a far better idea to soak up and disguise sweat than to block it.

CS as a result of ETS and Generalised Hyperhidrosis:

The main places ETS people suffer is down their back, torso, groin and legs. I would suggest products like laulas undershirts and polo shirts, www.sweat-help.com and Wrapps www.coolwrapps.com. Both of these products will deal with soaking up sweat by clever use of fabrics. I use both products and they certainly make life easier for me. Wrapps are also increasingly used by sportsmen and women, musicians etc as well as HH sufferers.

Please feel free to visit the site and dive into the forum conversations – or even just keep an eye out for competitions (we get to give away lots of free products) and hints and tips on disguising and dealing with your sweating.

I decided to split the blog from the testimonials to make everything easier to find.

Hydrosal website
Hydrosal customer testimonials
Forum link blog
Forum link testimonials

“Hi, I’m from Australia and I would like to say, I would pay whatever dollar to fix up my sweaty arm pit problem, and then I came across Hydrosal!. I just would like to say there is no other product that works as good as this. and I have tried every single product out there and this is by far the best! I will keep using this product until I stop having this problem. Thanks, Jason ”

Jason
“I would like to bring to your attention, that I have tried the product that my doctor has recommended Hydrosal. For the pass thirty years I suffered in complete embarrassment, severe sweating from the forehead, and other body areas.
This sweating was triggered by nervousness on my confrontation of an individual that I met, or dealt with on first time basis.
The more I realized I was sweating, the more severe it became. It was devastating for me, and I spoke to many doctors with really no feed back from them. Meeting Dr Benohanian was for me a miracle; Life has given me a second chance. Hydrosal is amazing and very easy to apply with almost 90 to 95 % effective rate for me. Keep up the good work and create more beneficial products like Hydrosal!! Thanks again. ”

Allan
“Thank you, Thank you, Thank you! I have suffered from excessive sweating as long as I can remember…..the last 10 years specifically, have been the worst. I was ready to have surgery to have my sweat glands removed in my arm pits as nothing seemed to work. My doctor called me 2 weeks ago to tell me about an article that she read in the paper about Hydrosal Professional. After the first 2 days it started to sting a little when I applied the gel, but I got over that fast when I realized that it was working. I just finished my 7 days and have not sweat at all in 5 days. I am absolutely thrilled and hope that others will try this too. I realize that sweating is an embarrassing issue and I myself didn’t talk about it much with other people, but it’s kind of obvious when you can see it through your clothing. Since I no longer have this problem I have been telling my friends and family about it because I know how difficult dealing with this issue is and how much it affects your life. I am surprised to hear how many other people have excessive sweating also. Thanks again and I will continue to spread knowledge about this great product! ”

Jennifer
“Before Hydrosal I would always have to worry about sweat stains in the shirts I used to wear. Now after using Hydrosal I can wear any color I want in any fabric. Hydrosal worked fast too; after 2 days I could already see the results – no more sweat stains. I highly recommend Hydrosal to anybody who has had it with those extremely embarrassing sweat stains and doesn’t want to worry about them anymore! ”

Julia
“My story began in high school. Whenever I had a big exam or had to do a presentation in class, I would start to perspire. I tried many different deodorants, changing deodorants almost every other day. I wore dark clothing, trying to mask my condition. I started purchasing only cotton garments as well in an attempt to hide the perspiration. When the condition was at its worst, I would place many tissues or a small towel under my shirt to contain the perspiration. I would have to change clothing once I arrived at an event due to the excessive perspiration. Ten years later, a friend of mine saw an Oprah show on “Hyperhydrosis” and how this was a known medical condition. From her information, I did some research online and found a doctor in Montreal that specialized in the treatment of Hyperhydrosis. The doctor prescribed “Hydrosal”. I put some on everyday for seven days before bed, and it worked! After that, I only need to apply the gel once a week and it continues to work. I’ve been using the gel for two months now. “Hydrosal” does not have any odor, has not caused any discomfort, and has removed my worries about public embarrassment. Thank you for helping me get over my embarrassing condition. ”

Sophia
“I am delighted to see that after 34 years of experience as a dermatologist, Valeo Pharma is bringing Hydrosal Professional to America. I have had the rare opportunity of treating over 7000 patients suffering from excessive sweating; the affected sites were the underarms, hands, feet,face and groins. Some of them were unquestionably candidates for surgery. Hydrosal, a new first line treatment for excessive sweating, consists of aluminum chloride hexahydrate in a proprietary gel base.Studies have demonstrated that a gel vehicle is better tolerated than an alcohol solution and that may be the reason why such preparations have improved efficacy and are better tolerated. I highly recommend this product as a first line treatment before considering Iontophoresis, Botox® injections or surgery. ”

Antranik Benohanian MD, FRCPC, FAAD

Dr. Benohanian is a Dermatologist at the Montreal University Hospital Center (Saint-Luc Hospital)
“I’ve had plantar hyperhidrosis since childhood, but figured I’d have to suffer through it. This winter my sweaty feet got so wet and cold that I got 2nd degree frostbite on two toes, so I became desperate to find something to help. I found Hydrosal Gel while researching iontophoresis online. I was skeptical but am thrilled with the results! Noticeable difference after two nights and I haven’t had to re-apply for two weeks now (plus, I’m in Hawaii where it’s much warmer than Calgary). My feet are sweat-free but the skin is not dehydrated or itchy. I’m so glad to have found this terrific product! Will also add that the service from Well.ca was great, along with the best price plus free-shipping. Thank you!! ”

well.ca customer
“It’s awesome – if you take any prescription medication and the side effect is that you are sweating buckets… well, this is a true life saver. Also a great thing to put on if you want to go out all night dancing as you will not sweat. I am sure the company can improve in the area of how often to apply. Apart from that, if you don’t take medication and just have hyperhydrosis, you would have to use it a lot less after the first week. ”

well.ca customer
“This stuff really works! I’ve had excessive sweating for years and had pretty much given up on finding a solution.

I tried Hydrosal gel and after a few days the sweating was gone. Now I only use it a few nights a week. Let’s say I stop using it for a few days. All I have to do is start using it again and by the 2nd night the sweating has stopped again. ”

well.ca customer
“I read on the net about this product and thought I would give it a go. I have a little bit of a face perspire issue in tight places like bars where people may be elbow to elbow, or job interviews with stress. I bought it, LOVE it! I use it only when needed before a situation and its all win. HIGHLY recommended and supplier is good also. ”

well.ca customer
“ I have never used any product that works as well as Hydrosal Gel. ”

well.ca customer
“ This stuff is a life saver! ”

well.ca customer

Hi everyone

We wanted to share this brief online survey with you. The University of Cardiff (Wales, UK) are running a survey regarding Hyperhidrosis and how it affects us and our lives. You can leave your email address if you like but it’s not required if you’d rather remain anonymous.

Please spare a couple of minutes and have a go at filling it in – it’s one simple page with a few questions to answer and it ultimately helps the University to help us. We like it when people take us and our sweating seriously!

Here’s the link, if you can’t click on it let me know and I’ll sort it out for you.

University of Cardiff Hyperhidrosis Survey

Link target http://www.zoomerang.com/Survey/WEB22CSWJ8BCX3
Forum link

Go on, take the ‘plunge’…

Very Sweaty Betty needs your support!

If you have been helped by anything that Very Sweaty Betty has been tirelessly doing for the Hyperhidrosis community over this past few years, PLEASE take 2 minutes to nominate us for a new TV programme.

If we were to be lucky enough to be selected, this programme would help us to raise a massive amount of awareness of Hyperhidrosis. Just think of what we could do with the advertising, how many more people we will be able to help through our Hyperhidrosis Awareness Campaign and what this would mean for the whole Hyperhidrosis community.

More awareness of Hyperhidrosis means so much for all of us. There would be more products, more research, more help, the medical profession taking this disease seriously and eventually all these things could even help progress in finding a cure one day. It also means less ignorance and more understanding – which is something that we could all do with. Knowledge is power.

There really aren’t many opportunities like this that come our way – so please click through to this page and email the makers of the tv programme to tell them about all the good work that VSB is doing and how much we would all benefit from this help and raising of awareness. We want everyone to know about Hyperhidrosis and YOU can help us to achieve our dream!

We’d like to extend a huge welcome to www.sweating.com and www.iontophoresis-device.com.

We are very happy to announce that they have made us their ‘official forum’!

Please have a look at their websites, they have so much information on Hyperhidrosis and Iontophoresis – they’re a very approachable company and very happy to answer any questions, suggestions and comments you may have on these subjects.

Please feel free to ask any questions in this forum (please start a new topic for each question) and they will answer them for you. Also any discussions on their products are welcome in this forum.

CALLING ALL TEENAGERS, CALLING ALL VSB TEENS!!!!!!

With spring springing and summer looming your all cramming the books and revising for your exams, some of you are in your final year.

How are you ALL coping? Is the added stress making your HH worse? Do you find yourself feeling alone and tired and sick of sweating?

Wanted to tell you all, YOU’RE NOT ALONE!

Here at VSB WE are here for you! We will give you the support you need and friendship and the tools and know how to get you by another day living with HH.

Get to know each other and share other interests, music, videos.

We provide a safe place for you all.

http://verysweatybetty.com/forum/viewtopic.php?f=46&t=1386

There are all sorts of ways you can become involved with taking control of your Hyperhidrosis, Anne found this today:

Take a look at what I stumbled upon today, makes a great read.

I am glad this is taking place.

http://verysweatybetty.com/forum/viewtopic.php?f=13&t=1120

www.verysweatybetty.com

www.coolwrapps.com

Hyperhidrosis is a skin disease.  It can be generalised or localised to specific parts of the body.  Hands, feet, armpits, and the groin area are among the most active regions of perspiration due to the relatively high concentration of sweat glands; however, any part of the body may be affected.

Hyperhidrosis can also be classified depending on whether it is a congenital (hereditary) or an acquired trait.  Primary hyperhidrosis is found to start during adolescence or even before and seems to be inherited as a genetic trait.  Primary hyperhidrosis must be distinguished from secondary hyperhidrosis, which can start at any point in life.  The latter form may be due to a disorder of the thyroid or pituitary gland, diabetes mellitus, tumors, gout, menopause, certain drugs or mercury poisoning.  It can be a symptom  of temporary illnesses like colds and ‘flu or hormonal changes such as periods or menopause.  Hyperhidrosis can also be divided into Palmar/Plantar (symptomatic sweating of primarily the hands or feet), Axilliary (armpit sweating), Facial/Cranial (sweating from the face/head region), Gustatory (sweating whilst eating/digesting a meal) or generalised hyperhidrosis which covers sweating from any other area in your body.

Everybody sweats, it’s a normal function which serves to cool us down so we don’t overheat.  Hyperhidrosis is caused by an overactive (ie broken) thermal regulator (the bodies thermostat).  In the simplest terms, in a Hyperhidrotic’s body, their thermostatic control is stuck on the hottest setting.

A medical diagnosis should always be sought, but if you sweat to an excessive level, there are now many ways of dealing with it.

About Sweaty Betty.
We are a small group of normal people who just happen to sweat a lot.  We’re not alone – millions of people worldwide suffer from this acutely embarrassing  and socially isolating condition, but, because of the negativity and misconceptions surrounding sweating and being sweaty, they attempt to keep it to themselves and suffer in silence.  As with all taboo issues, it only takes a few like-minded people to get together to blow a taboo wide apart and tell it how it really is.  Hence www.verysweatybetty.com was born.

We are committed to raising awareness of Hyperhidrosis and dispel the stigma and ignorance surrounding sweat and sweating.

Don’t allow your sweat glands to control your life any longer, please join us and find out how you can take control and start living your life again.

Our links:
www.youtube.com/verysweatybetty
www.twitter.com/verysweatybetty
www.facebook.com/betty.sweaty

Hyperhidrosis, or excessive sweating, is a skin disease which produces a lot of unhappiness.  It is estimated by the medical profession that 2-3% of people all around the world suffer from excessive sweating.  Non-medically speaking, the figure could easily be far, far higher.  In our experience, many people only find out they have Hyperhidrosis because they stumble across the name of it by accident.  Many people don’t want to bother their doctor because they think it’s ‘just them’.  There are many reasons why people can go throughout life and never mention it to anybody. Read the rest of this entry »